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席汉氏综合征并发尿崩症者很少,对其ADH 机能的研究则报道更少,作者对16例席汉氏综合征 及17例正常女性作了“禁水试验”,以评价其ADH 机能,对有肾上腺皮质及甲状腺功能低下者,首先 进行替代治疗,予以纠然后试验,方法为:晚 7时开始禁止饮水,次月晨7时每隔1小时收集尿 液标本一次,测渗透压,当相邻两次标本的渗透压 相差<30mOsm/kg,即认为达到了最大尿液浓缩 力,此时采血测血浆渗透压,对反渗透压低于600 mOsm/kg者,给予去氨加压素(desmopressin) 20μg,1小时后再次取尿测渗透压,以观察其变 化。
Few patients with Sheehan’s syndrome complicated by diabetes insipidus have reported much less about ADH function. The authors performed a water exclusion test for 16 cases of Han’s syndrome and 17 normal women to evaluate their ADH. Function, for those with adrenal cortex and hypothyroidism, first perform alternative treatment, correct and then test, by: 7 o’clock in the evening began to prohibit drinking water, the next month at 7 o’clock every hour to collect urine specimen once, measure osmotic pressure When the difference between the osmotic pressures of two adjacent specimens is less than 30 mOsm/kg, it is considered that the maximum urine concentrating force is reached. At this time, the plasma osmotic pressure is measured, and when the reverse osmotic pressure is lower than 600 mOsm/kg, deamination and pressure are applied. 20 μg of desmopressin was taken again after 1 hour to observe the change.