本文用G显带技术对15例原发性肝癌实体瘤作细胞遗传学研究。结果表明肝癌细胞染色体数以非整倍体为主,尤以亚二倍体和亚三倍体为多。各例均出现结构异常的染色体,对其中出现频率较高的20个标记染色体作了简要描述,并提及国内己发表的人肝癌细胞株染色体情况。结果提示某些染色体的断裂可能与肝癌的发生有一定关联。 In this paper, 15 cases of solid tumors of primary liver cancer were studied by G-banding technique. The results showed that the chromosome number of liver cancer cells was mainly aneuploid, especially sub-diploid and sub-triploid. In each of the cases, structurally abnormal chromosomes were present. A brief description was made of the 20 marker chromosomes with a high frequency of occurrence, and the chromosomes of human liver cancer cell lines that have been published in China were mentioned. The results suggest that the breakage of certain chromosomes may be associated with the occurrence of liver cancer.