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长期以来,人们就发现动脉粥样硬化与高胆固醇血症和高甘油三酯血症并存,且多有遗传性.但是,胆固醇(Ch)和甘油三酯(Tg)均是与其它脂类和蛋白质结合在一起,以脂蛋白的形式存在和运输的.从而,在动脉粥样硬化的研究领域中,经历了从测定血浆中胆固醇和甘油三酯含量到测定血浆中脂蛋白的过程,早已长足直入测定血浆中载脂蛋白(Apo)的研究时期.目前,已经在分子水平确定出某些Apo基因和脂蛋白受体基因异常在动脉粥样硬化发生过程中的作用. Apo是动脉粥样硬化的危险因子血浆中乳糜微粒(CM)和极低密度脂蛋白
It has long been known that atherosclerosis coexists with hypercholesterolemia and hypertriglyceridaemia and is often hereditary. However, both Cholesterol (Ch) and triglyceride (Tg) Proteins bind together and are present and transported as lipoproteins.Thus, the process of measuring cholesterol and triglyceride levels in plasma to measuring plasma lipoproteins has long since gone through the art of atherosclerosis Straight into the study period for determination of plasma apolipoprotein (Apo) .At present, the role of certain Apo and lipoprotein receptor gene abnormalities in the development of atherosclerosis has been established at the molecular level.Apo is an atherosclerosis The risk factors for plasma chylomicrons (CM) and very low density lipoprotein