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采用白细胞介素-2体外激活的LAK细胞联合放疗,对2例牙龈癌、1例颊粘膜癌、2例上颌窦癌进行治疗,均有明显疗效。其中1例经CT及病理组织证实肿瘤组织钙化成骨组织,1例转移性淋巴结吸收。治疗前后免疫功能测定:Leu11(14.6±3.7/25.2±5.0)、Leu7(13.5±2.5/25.8±3.2)、OKM,(17.6±5.2/31.3±12.5)阳性细胞率明显增加(P<0.01),酸性白血球总数(109.0±107.8/1704.1±773.8)增加有显著性意义(P<0.01),IgM(82.0±10.5/120.0±20.6)也表现为增高。
LAK cells combined with radiotherapy activated by interleukin-2 in vitro had obvious curative effect on 2 cases of gingival cancer, 1 case of buccal mucosal cancer and 2 cases of maxillary sinus cancer. One case was confirmed by CT and pathological tissue calcification of tumor tissue into bone tissue, 1 case of metastatic lymph node absorption. Immunological function before and after treatment: Leu11 (14.6±3.7/25.2±5.0), Leu7 (13.5±2.5/25.8±3.2), OKM, (17.6 ±5.2/31.3±12.5) The positive cell rate was significantly increased (P<0.01), and the total number of acidic leukocytes (109.0±107.8/1704.1±773.8) was significantly increased. Significance (P<0.01), IgM (82.0±10.5/120.0±20.6) also showed an increase.