论文部分内容阅读
检测27例临床甲状腺正常婴儿肝炎综合征患儿血清甲状腺激素浓度,从中发现无论有无并发症,血清T_3均值降低,rT_3升高,FT_3I降低,与正常婴儿对照组比较,有极显著差别(P<0.01),血清T_4、TSH、MAA和FT_4I均值与正常婴儿对照组无差别。血清T_3,rT_3和FT_3I均值与血清胆红素水平相关:随病情与肝损害改善,血清T_3和rT_3可趋于正常。婴儿肝炎综合征患儿甲状腺功能试验异常主要因素与外周组织T_4转化成T_3减少有关。患儿血清T_3,T_4均极低,尤其T_4明显下降时,提示预后不良。
Serum thyroid hormone concentrations were measured in 27 cases of normal thyroid normal infantile hepatitis syndrome. Serum levels of thyroid hormone (T_3), rT_3 and FT_3I were decreased in both groups with or without complication <0.01). There was no difference between the mean of serum T 4, TSH, MAA and FT 4I in normal infants. Serum T_3, rT_3 and FT_3I mean serum bilirubin levels: with the disease and liver damage improved, serum T_3 and rT_3 may be normal. The main factor of abnormal thyroid function test in infants with hepatitis syndrome is related to the reduction of T_4 in peripheral tissue into T_3 reduction. Children with serum T_3, T_4 are extremely low, especially when T_4 significantly decreased, suggesting a poor prognosis.