内分泌治疗作为各期乳腺癌全身治疗的一个切实可行的重要手段，已引起了广泛的重视。在此，我们将其进展作一简述。1 内分泌治疗发展史Beatson[1]1896年在Lancet上首次报道，进展期乳腺癌绝经前患者行卵巢切除后肿块消退。在20世纪前半叶，对于不能手术及复发的绝经前乳腺癌患 Endocrine therapy has been widely considered as a practical and important means for the systemic treatment of breast cancer in various stages. Here, we will make a brief statement of its progress. A history of the development of endocrine therapy Beatson [1] in 1896 Lancet for the first time reported that premenopausal patients with advanced breast cancer after ovarian resection after lump subsided. In the first half of the 20th century, premenopausal breast cancer patients who could not be operated or relapsed