目的探讨Kimura病的临床症状、体征、相关病理学检查及实验室检测,并对其诊断、鉴别诊断及治疗的方法进行相关讨论总结。方法回顾性分析11例就诊于耳鼻咽喉头颈外科及皮肤科的Kimura病患者的临床相关资料,总结其实验室检查及病理检查的特点,同时对比分析经手术治疗及保守治疗后的疗效。结果 11例Kimura患者年龄平均39岁,均为男性,分别发生于耳前、耳后、颈部、颌下等部位,临床表现无显著特异性,常表现为病变区的无痛性渐近性肿胀,病理学表现为大量淋巴组织增生,有淋巴滤泡形成,并见有多量嗜酸性粒细胞浸润。实验室检查见外周血嗜酸性粒细胞升高,血清Ig E升高。结论 Kimura病的诊断主要依据临床表现、实验室检查及病理检查。由于该病罕见、无特异性临床表现、病程长、慢性起病,易导致漏诊。对于耳鼻咽喉头颈外科医生来说,应具备相关知识储备,通过主诉、视诊、实验室检查及病理活检等给予早期诊断,避免误诊漏诊。Kimura病可通过手术切除或激素、放射治疗等多种方式相应控制肿物的扩散及复发。 Objective To investigate the clinical symptoms, signs, related pathological examination and laboratory tests of Kimura disease and to discuss the methods of diagnosis, differential diagnosis and treatment. Methods The clinical data of 11 patients with Kimura disease treated in otorhinolaryngology head and neck surgery and dermatology were retrospectively analyzed. The characteristics of laboratory examination and pathological examination were summarized. The curative effect after surgical treatment and conservative treatment were compared. Results The average age of 11 Kimura patients was male, all of whom were male. They occurred in the front of the ear, ear, neck and submandibular. The clinical manifestations were not significantly specific and often showed painless asymptotic Swelling, pathology showed a large number of lymphoid hyperplasia, lymphoid follicles, and see how much eosinophil infiltration. Laboratory tests showed increased peripheral blood eosinophilia, elevated serum Ig E. Conclusion The diagnosis of Kimura disease mainly based on clinical manifestations, laboratory tests and pathological examination. As the disease is rare, no specific clinical manifestations, long duration, chronic onset, easily lead to missed diagnosis. For otolaryngology head and neck surgeons, should have the relevant knowledge reserve, through the chief complaint, visual examination, laboratory tests and biopsy to give early diagnosis, to avoid misdiagnosis. Kimura disease can be controlled by surgical excision or hormone, radiation therapy and other means of proliferation and relapse.