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一氧化氮(nitric oxide,NO)是内皮舒张因子(endothelium derived relaxing factor,EDRF)的活性形式,其主要由血管内皮产生与释放。随着NO研究的不断深入,其在休克时的变化及其在休克发病过程中的作用日趋受到关注。本文就近年来对NO的研究及其与休克关系的报道作简要叙述。
Nitric oxide (NO) is an active form of endothelium derived relaxing factor (EDRF), which is mainly produced and released by the vascular endothelium. With the deepening of NO research, its changes in shock and its role in the pathogenesis of shock has drawn increasing attention. This article briefly describes the research on NO and its relationship with shock in recent years.