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目的评估中性粒细胞/淋巴细胞比率(NLR)在幕上自发性脑出血中的临床诊断价值。方法本次研究人群仅限于年龄≥35岁的幕上自发性脑出血患者。研究中采用GOS评分量表量化临床结果,同时根据患者CT扫描情况,使用abc/2方法计算幕上自发性脑出血的出血量。使用logistic回归模型和生存分析来分析独立因素与临床结果的相关性。结果 130例幕上自发性脑出血患者中,30 d内预后效果不良的患者NLR值高于预后效果良好的患者(13.52±14.65 vs 5.82±5.21;P=0.002)。NLR分界值为0.74时,其敏感度为0.611,特异度为0.797。NLR与血肿体积有较强的相关性(r=0.203,P=0.023)。结论 NLR与幕上自发性脑出血患者30 d的GOS评分和出血量呈正相关。
Objective To evaluate the clinical value of neutrophil / lymphocyte ratio (NLR) in supratentorial intracerebral hemorrhage. Methods This study population was limited to patients with supratentorial spontaneous intracerebral hemorrhage ≥35 years of age. The GOS scale was used in the study to quantify the clinical results. At the same time, the abc / 2 method was used to calculate the amount of hemorrhage due to supratentorial ICH according to the CT scan of the patients. Logistic regression models and survival analyzes were used to analyze the association of independent factors with clinical outcomes. Results Among 130 patients with supratentorial ICH, patients with poor prognosis within 30 days had higher NLR than those with good prognosis (13.52 ± 14.65 vs 5.82 ± 5.21; P = 0.002). When the NLR cut-off value was 0.74, the sensitivity was 0.611 and the specificity was 0.797. NLR and hematoma volume have a strong correlation (r = 0.203, P = 0.023). Conclusion NLR was positively correlated with GOS score and amount of bleeding at 30 days in patients with supratentorial intracerebral hemorrhage.