论文部分内容阅读
目的探讨食管癌患者外周血树突状细胞(DC)水平对预后的影响。方法采用流式细胞术对40例食管癌患者(A组)以及30例健康对照者(B组)外周血DC水平进行检测。对食管癌患者行3年随访。分析外周血树突状细胞水平与食管癌分期及术后生存率之间关系。结果A组患者外周血DC水平显著低于B组(P<0.05)。外周血DC水平高一些的食管癌患者3年生存率显著高于低者(50%vs.30%)。DCs水平与肿瘤分化程度无显著差异。结论食管癌外周血DC水平高的患者预后较好。
Objective To investigate the effect of peripheral blood dendritic cells (DCs) on prognosis in patients with esophageal cancer. Methods Flow cytometry was used to detect peripheral blood DC levels in 40 patients with esophageal cancer (group A) and 30 healthy controls (group B). Patients with esophageal cancer for 3 years follow-up. To analyze the relationship between peripheral blood dendritic cells and esophageal cancer staging and postoperative survival rate. Results A group of patients with peripheral blood DC levels were significantly lower than the B group (P <0.05). The 3-year survival rate of esophageal cancer patients with higher DC level was significantly higher than that of the lower (50% vs. 30%). DCs levels and tumor differentiation no significant difference. Conclusion The prognosis of patients with high esophageal cancer peripheral blood DC level is good.