许多肿瘤都发现存在微卫星的杂合性丢失（ｌｏｓｓｏｆｈｅｔｅｒｏｚｙｇｏｓｉｔｙ，ＬＯＨ）现象［１］。基因丢失的部分往往存在抑癌基因。白血病常有染色体易位，形成易位的断裂点区域抑癌基因的丢失可能与血细胞恶变的发生有关。我们用分布在不同染色体上断裂点区域... Loss of heterozygosity (LOH) in microsatellites is found in many tumors [1]. Loss of genes is often the presence of tumor suppressor genes. Leukemia often has chromosomal translocations, and the loss of tumor suppressor genes in the formation of translocation breakpoint regions may be associated with the development of hematological malignancies. We use the distribution of breakpoints on different chromosomes...