论文部分内容阅读
目的 :观察促红细胞生成素 (r Hu EPO)对慢性肾功能衰竭红细胞免疫功能的影响。方法 :分析 35例慢性肾衰患者用 r Hu FPO前后红细胞 C3b受体花环百分率的变化及其与红细胞 SOD和血浆过氧化脂质浓度的相关性。结果 :用 r Hu FPO的慢性肾衰患者的红细胞 C3b受体花环百分率明显增加 ,并与红细胞 SOD呈正相关 ,与血浆过氧化脂质呈负相关。结论 :r Hu FPO能够提高红细胞免疫功能 ,这与提高红细胞 SOD、减少脂质过氧化损伤相关
Objective: To observe the effect of r Hu EPO on erythrocyte immune function in patients with chronic renal failure. Methods: The percentage changes of rosette C3b receptor rosette in patients with chronic renal failure before and after rhu FPO were analyzed, and their correlations with erythrocyte SOD and plasma lipid peroxidation were analyzed. RESULTS: The percentages of rosette C3b receptors in chronic renal failure patients with r Hu FPO were significantly increased, positively correlated with erythrocyte SOD and negatively correlated with plasma lipid peroxidation. CONCLUSION: r Hu FPO can improve erythrocyte immune function, which is related to the increase of erythrocyte SOD and the reduction of lipid peroxidation injury