本文应用淋巴细胞单克隆抗体,发现扩张型心肌病(DCM)外周血淋巴细胞亚群明显异常;同时用短寿命细胞法发现DCM 的抑制细胞功能明显减低,并与心功能不全之间存在明显的正相关。还发现DCM 患者循环中抗心肌抗体对培养的心肌细胞具有明显的细胞毒效应。DCM 可能是一个与病毒性心肌炎及遗传免疫缺陷有关的自身免疫病. In this paper, monoclonal antibodies to lymphocytes was found in patients with dilated cardiomyopathy (DCM) peripheral blood lymphocyte subpopulations was significantly abnormal; while using short-lived cell method was found that DCM inhibition of cell function was significantly reduced, and there is significant between the cardiac dysfunction Positive correlation. It was also found that anti-myocardial antibodies in circulating DCM patients had a significant cytotoxic effect on cultured cardiomyocytes. DCM may be an autoimmune disease associated with viral myocarditis and genetic immunodeficiency.