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非甾体抗炎药 (ＮＳＡＩＤｓ)具有止痛、抗炎的作用 ,其中阿司匹林还有抗血栓形成的作用 ,但ＮＳＡＩＤｓ有明显的胃肠道副作用。选择性环氧合酶 (ＣＯＸ) 2抑制剂的上市 ,意味着可以为风湿病患者提供对胃肠道有较少副作用的治疗。选择性ＣＯＸ 2抑制剂可使前列腺素 (ＰＧ)Ｉ2
Non-steroidal anti-inflammatory drugs (NSAIDs) have analgesic and anti-inflammatory effects. Aspirin also has antithrombotic effect, but NSAIDs have obvious gastrointestinal side effects. The introduction of selective cyclooxygenase (COX) 2 inhibitors means that rheumatism patients can be treated with fewer side effects on the gastrointestinal tract. Selective COX 2 inhibitors make prostaglandin (PG) I2