Ph~1阳性慢粒患者在原始细胞危象时,能同时见到淋巴性和髓性原始细胞,而在Ph~1阴性急性白血病通常少见。白血病原始细胞同时表现淋巴性和髓性标记则属罕见。作者报告3例病人诊断时的白血病原始细胞有淋巴性和髓性标记的混合表现,其细胞化学特征提示急非淋(ANLL),而免疫学表型为典型急淋(ALL)。 Patients with Ph ~ 1-positive chronic myeloma can see both lymphoid and myelogenous blast cells in the primal cell crisis, but are rare in Ph-1-negative acute leukemias. It is rare for leukemia blasts to display both lymphoid and myeloid markers. The authors report a mixed presentation of lymphoid and myeloid leukemia blasts in 3 patients at the time of diagnosis. The cytochemical characteristics of the leukemia blasts prompted ANLL, whereas the immunological phenotype was typical acute lymphoblastic leukemia (ALL).