近年来,关于健康人和病人的姊妹染色单体交换(SCE)异常这个问题已引起人们很大的注意。尽管SCE的机制尚未完全弄清,但SCE 分析对于监视DNA 的损伤和修复方面提供了极好的参数。一些研究的结果表明,SCE 频率的升高是由于致癌剂或诱变剂的作用引起的。据报道乳腺癌病例比对照者的SCE 频率明显升高,这就提示SCE 可能作为临床前期早期发现癌症的标记者。作者尚未发现在子宫颈癌方面有类似的研 In recent years, the problem of sister chromatid exchange (SCE) abnormalities in healthy people and patients has attracted much attention. Although the mechanism of SCE has not been fully understood, SCE analysis provides excellent parameters for monitoring DNA damage and repair. Some studies have shown that the increase in SCE frequency is due to the effects of carcinogens or mutagens. It has been reported that the frequency of SCE in breast cancer cases is significantly higher than that of controls, suggesting that SCE may be used as a marker for early detection of cancer in the preclinical stage. The author has not found a similar study in cervical cancer