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线粒体是一种细胞器，广泛存在于除红细胞以外的大多数细胞体内，同时也是细胞进行氧化磷酸化、三羧酸循环及氧化呼吸链的主要场所，产生 ATP，提供细胞活动所需能量，同时线粒体也参与细胞代谢的多个环节，如细胞增殖、凋亡等。近年来，线粒体与细胞调控对疾病的发生、发展成为潜在的研究热点。因此，明确线粒体在细胞调控中的作用机制，以便更好地认识及指导对相关性疾病的治疗具有重要意义。“,”Mitochondria is a cell organelle,which widely exists in the majority of the cells except red blood cells,at the same time,it is an important place for cell to carry out oxidative phosphorylation ,three tri-carboxylic acid cycle and oxidative respiratory chain , producing ATP for the requirement of cell activity , moreover,mitochondria also participates in multiple processes of cell metabolism ,such as cell proliferation, apoptosis,etc.In recent years,the mitochondria and cell regulation on the occurrence of diseases has become a potential research hotspot.Therefore clarifying the mechanism of cell regulation in mitochondria has a great significance for understanding and guiding the treatment of associated diseases.