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目的:探讨T4胃癌根治切除术患者的生存情况及预后影响因素。方法:对2007年1月—2011年12月收治的有完整临床及随访资料的183例T4胃癌根治切除术患者行回顾性分析。结果:全组患者1,3,5年累积生存率分别为92%,60%,42%,单因素分析显示,淋巴结转移率、pN分期、肿瘤浸润深度、组织学类型与患者术后生存率有关(均P<0.05);多因素分析显示,淋巴结转移率、pN分期、肿瘤浸润深度是影响患者预后的独立危险因素(均P<0.05)。结论:淋巴结转移率、pN分期、肿瘤浸润深度是影响T4胃癌根治切除术患者生存的独立预后因素。
Objective: To investigate the survival and prognosis of patients undergoing radical resection of gastric cancer T4. Methods: A retrospective analysis of 183 patients with radical gastrectomy for gastric cancer who had complete clinical and follow-up data from January 2007 to December 2011 was performed retrospectively. Results: The cumulative survival rates at 1, 3 and 5 years were 92%, 60% and 42% respectively. Univariate analysis showed that lymph node metastasis, pN stage, depth of tumor invasion, histological type and postoperative survival rate (All P <0.05). Multivariate analysis showed that lymph node metastasis rate, pN stage and tumor invasion depth were independent risk factors for prognosis of patients (all P <0.05). Conclusion: Lymph node metastasis rate, pN stage and tumor infiltration depth are the independent prognostic factors for the survival of patients undergoing radical resection of gastric cancer.