美国Bayler医科大学和美国Phillips公司在1985年11月设立的美国Oncos公司向保险产业销售利用单克隆抗体从唾液鉴别吸烟者的检查箱。该公司预计非吸烟者的人身保险费用比吸烟者优惠5～15％,所以,保险企业需要鉴别出吸烟者的检查箱。该公司经理Peter C.Ulrich指出:“1987年1月向有关分析研究所销售首批制品,一年卖出100～200万美元。另外,计划在1987年年中使使用方便的浸渍片方式商品化。” American Oncos company, established by American Bayler Medical University and Phillips Company in November 1985, sold to the insurance industry the use of monoclonal antibodies to identify smokers’ check boxes from saliva. The company expects non-smokers to have a 5 to 15% discount on personal insurance costs compared to smokers. Therefore, insurance companies need to identify the smokers’ inspection boxes. The company’s manager, Peter C. Ulrich, pointed out: "The first batch of products was sold to relevant analytical institutes in January 1987, and sold between US$100 and US$2 million a year. In addition, it is planned to use a convenient dipstick product in mid-1987. Change.”