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目的探讨经肝动脉化疗栓塞(TACE)结合立体定向体部伽玛刀治疗肝癌的临床疗效。资料与方法将原发中晚期肝癌52例分为A、B两组。A组:30例,采用单纯TACE术,且行TACE术均在2次以上;B组:22例,采用TACE+体部伽玛刀治疗,先行TACE术1～3次后,再进行体部伽玛刀放射治疗,单次剂量为36～44 Gy。并观察比较肿瘤治疗后的近期疗效、患者生存期及并发症。结果A、B两组近期治疗总有效率分别为56.7%(17/30)和86.3%(19/22);患者1年生存率分别为70.0%和90.9%,中位生存期为11.2个月和15.5个月;两组并发症无明显差别。结论TACE结合体部伽玛刀治疗原发性肝癌是一种安全、有效的方法。
Objective To investigate the clinical efficacy of transcatheter arterial chemoembolization (TACE) combined with stereotactic body gamma knife in the treatment of liver cancer. Materials and Methods The primary liver cancer in 52 cases were divided into A and B groups. In group A, 30 patients were treated with simple TACE, and TACE was performed more than twice. In group B, 22 patients were treated with TACE plus body gamma knife. TACE was performed 1 ~ 3 times before body gamma Knife radiation therapy, a single dose of 36 ~ 44 Gy. And observed and compared the short-term efficacy of cancer treatment, patient survival and complications. Results The total effective rates of the two groups were 56.7% (17/30) and 86.3% (19/22) respectively. The 1-year survival rates were 70.0% and 90.9%, respectively. The median survival time was 11.2 months And 15.5 months; no significant difference between the two groups of complications. Conclusion TACE combined with gamma knife treatment of primary liver cancer is a safe and effective method.