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对用放射受体分析(RRA)法测定血浆中α1-肾上腺素受体拮抗剂盐酸哌唑嗪浓度与先前应用的HPLC法进行了比较研究。RRA法取9~11kg的成年Beasle狗禁食过夜,按2.39μmol·kg-1喂以盐酸哌唑嗪溶液,在0.5~8h内取血样测定,同法从12名接受1.79~3.59μmol·d-1盐酸哌唑嗪治
A comparative study of the plasma concentrations of prazosin hydrochloride using the radioimmunoassay (RRA) method and the previously used HPLC method was performed. RRA method to take 9 ~ 11kg adult Beasle dog fasted overnight, according to 2.39μmol · kg-1 fed prazosin hydrochloride solution within 0.5 ~ 8h blood samples were taken, the same method from 12 to accept 1.79 ~ 3.59μmol · d-1 prazosin hydrochloride treatment