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脑卒中为主要致死致残慢病之一,尤其是缺血性卒中更为多发。而先天性心脏病(CHD)通过其未闭导管、异常分流、心律失常和其他心血管系统异常,明显增加缺血性卒中风险。既往关于年轻成人及儿童CHD患者与继发缺血性卒中风险间关系尚不清楚,现就此进行大样本相关调研对照分析。受试对象为25 985例年轻成人及儿童CHD患者,均龄28.6岁,为病例组;259 750例年轻成人及儿童非CHD者,均龄29.5岁,系对照组。两组性别分布大致相仿。在病例组中均
Stroke is one of the major chronic diseases caused by death, especially ischemic stroke. Congenital heart disease (CHD) significantly increases ischemic stroke risk through its patent ductus, abnormal shunts, arrhythmias, and other cardiovascular disorders. In the past, the relationship between CHD in young adults and children and the risk of secondary ischemic stroke was not clear. A comparative analysis of large sample studies was conducted. Subjects were 25,985 young adults and children with CHD, both of whom were 28.6 years old and were in the case group; 259,750 young adults and children with non-CHD, mean age 29.5 years old, the control group. The two groups have roughly the same gender distribution. In the case group are