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在体外实验的基础上,我们用重组人肿瘤坏死因子(rHTNF)单独或联合更生霉素(KSM)对人卵巢癌裸鼠移植瘤模型进行了8个周期的实验治疗。结果显示,rHTNF可显著地抑制移植瘤生长:rHTNF与KSM联合呈现出较强的协同作用,治疗效果更好。
On the basis of in vitro experiments, we used the recombinant human tumor necrosis factor (rHTNF) alone or in combination with KSM to perform 8 cycles of experimental treatment on human ovarian cancer xenograft model in nude mice. The results showed that rHTNF can significantly inhibit the growth of transplanted tumors: rHTNF combined with KSM showed a strong synergistic effect, and the treatment effect was better.