幽门螺杆菌(Helicobacter pylori,Hp)是一种螺旋状、革兰染色阴性、微需氧细菌,进入人胃在低pH值环境中生长繁殖。据报道,在发达国家40%成人感染Hp,发展中国家成人Hp感染率高达90%[1,2]。Hp主要定植于人胃黏膜,是导致慢性萎缩性胃炎、胃黏膜不典型增生等癌前病变发生的重要因素 Helicobacter pylori (Hp) is a helical, Gram-negative, microaerophilic bacterium that enters the human stomach and grows in low pH environments. According to reports, 40% of adults in developed countries are infected with Hp, and the adult Hp infection rate in developing countries is as high as 90% [1, 2]. Hp mainly colonizes the human gastric mucosa and is an important factor leading to the occurrence of precancerous lesions such as chronic atrophic gastritis and gastric dysplasia.