门静脉高压规范化诊疗应强调早筛早诊、三级预防、急诊救治等链条式全病程管理。针对临床实践中关键科学问题或热点难点问题开展高质量研究并转化应用，是实现门静脉高压患者个体化、精准化管理的有效手段。纷繁复杂的门静脉高压全病程管理需要依靠一个个终点明确、严格纳排、良好对照的临床研究，加之一个个有效转化、客观评价、良好推广的产品技术，才有可能不断优化现行诊疗实践——至繁归于至简。“,”The standardized diagnosis and treatment of portal hypertension should emphasize the chain-type full-course management including early screening, early diagnosis, tertiary prevention, and emergent management. The high-quality research and translational applications of key scientific or hot issues in clinical practice are effective means to achieve individualized and precise management of patients with portal hypertension. Full-course management of portal hypertension is complex and complicated. It is necessary to initial the clinical research with clear endpoint, strict criterion, and appropriate reference. Meanwhile, the technological product with effective translation, objective evaluation, and wide promotion is also indispensable for optimizing the current practice continuously: Simplicity is the ultimate sophistication.