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目的:研究孕早期米非司酮联合米索前列醇流产的效果。方法:将2012年3月-2014年4月期间在我院接受早孕流产的100例患者纳入研究,根据流产方式不同分为两组,观察组患者给予米非司酮口服联合米索前列醇阴道给药,对照组患者给予米非司酮联合米索前列醇口服,比较两组患者的流产效果。结果:观察组患者完全流产45例、多于对照组的31例,不完全流产和流产失败分别为4例和1例,少于对照组的12例和7例;观察组患者用药后流产时间、出血持续时间、月经恢复时间分别为3.84±0.56d、13.84±1.94d、32.84±4.57d,短于对照组的5.17±0.68d、19.57±2.53d、44.91±6.02d。结论:米非司酮口服联合米索前列醇阴道给药有助于改善流产效果、缩短流产时间和术后出血持续时间,是早孕流产的理想方法。
Objective: To study the effect of mifepristone combined with misoprostol abortion in early pregnancy. Methods: One hundred patients with early pregnancy miscarriage in our hospital from March 2012 to April 2014 were enrolled in the study. According to the different abortion methods, the patients were divided into two groups. Patients in the observation group were given oral mifepristone combined with vaginal misoprostol The patients in the control group were given mifepristone plus misoprostol orally, and the abortion effect was compared between the two groups. Results: In the observation group, 45 cases of complete abortion, more than the control group of 31 cases, incomplete abortion and abortion failure were 4 cases and 1 case, less than the control group of 12 cases and 7 cases; observation group patients after treatment of abortion time , Duration of bleeding and menstrual recovery were 3.84 ± 0.56d, 13.84 ± 1.94d and 32.84 ± 4.57d, respectively, which were shorter than those of the control group (5.17 ± 0.68d, 19.57 ± 2.53d, 44.91 ± 6.02d). Conclusion: The oral administration of mifepristone combined with misoprostol vaginally will help to improve the abortion effect, shorten the time of abortion and the duration of postoperative bleeding, which is an ideal method for abortion of early pregnancy.