芳基硫酸酯酶是一组能水解各种硫酸酯的同工酶,由于与多种遗传代谢病有关,在人类遗传学上具有一定的重要性。近年来,芳基硫酸酯酶的生化及临床研究有了深入的进展,本文就近几年临床研究的进展作一综述。先天缺乏芳基硫酸酯酶的最常见病是异染性脑白质营养不良,从分子生物学角度探 Aryl sulfatase is a group of isoenzymes that can hydrolyze various sulfate esters and is of importance in human genetics because it is associated with a variety of genetic metabolic diseases. In recent years, the biochemical and clinical research of aryl sulfatase has made in-depth progress. This article reviews the progress of clinical research in recent years. The most common disease that lacks aryl sulfatase is congenital white matter malnutrition, and explored from the perspective of molecular biology.