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目的评价南京地区先天性甲状腺功能减低症(CH)患儿7岁以前的肥胖发生状况。方法回顾分析在我院确诊并长期随访的CH患儿7岁以前的肥胖发生状况。采用最新中国九市儿童身高(长)标准体重作为参照标准。评价结果与患儿疾病相关指标进行相关分析。结果 CH患儿发生超重及肥胖的几率较正常健康儿童均有显著增加。而出生体重,TSH、T3、T4、FT3及FT4初始值与患儿肥胖的发生无明显相关性。结论 CH患儿发生肥胖的几率较正常健康儿童增加,与疾病的严重程度无明显相关性。
Objective To evaluate the prevalence of obesity before birth in children with congenital hypothyroidism (CH) in Nanjing. Methods The incidence of obesity in CH children diagnosed and followed up for a long time in our hospital before the age of 7 was retrospectively analyzed. Using the latest nine Chinese children’s height (long) standard weight as a reference standard. Evaluation results and disease-related indicators of disease-related analysis. Results The incidence of overweight and obesity in CH children was significantly higher than that in normal healthy children. The birth weight, TSH, T3, T4, FT3 and FT4 initial values and children with obesity no significant correlation. Conclusion The incidence of obesity in children with CH is higher than that in normal healthy children and has no significant correlation with the severity of disease.