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本文用染色计数法测定了正常妇女早期妊娠的NK细胞活性,以及人类绒毛膜促性腺激素(hcG)、孕酮、已烯雌酚在不同浓度下对NK活性的影响。结果表明:①妊娠早期NK活性明显低于正常妇女(p<0.001)。②hcG在10IU/ml及100IU/ml两浓度下对NK活性都有明显抑制作用(p<0.05,p<0.001)。③孕酮、已烯雌酚在10μg/ml下对NK活性有明显抑制作用(p<0.01)。在0.1μg/ml下对NK活性无明显抑制作用(p<0.05)。
In this paper, the NK cell activity of normal pregnant women in early pregnancy and the effect of human chorionic gonadotropin (hcG), progesterone and diethylstilbestrol on NK activity at different concentrations were determined by the method of dyeing counting. The results showed that: ① early pregnancy NK activity was significantly lower than normal women (p <0.001). ② hcG at 10 IU / ml and 100 IU / ml two concentrations of NK activity were significantly inhibited (p <0.05, p <0.001). ③ progesterone, diethylstilbestrol at 10μg / ml of NK activity was significantly inhibited (p <0.01). No significant inhibition of NK activity at 0.1 μg / ml (p <0.05).