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采用昆明系小鼠，全身照射低剂量Ｘ射线，剂量为５０～５００ｍＧｙ，剂量率为１２．５ｍＧｙ／ｍｉｎ，照射后２４ｈ，检测松果腺ｃＡＭＰ含量变化，结果表明５０～１００ｍＧｙＸ射线全身照射可使松果腺ｃＡＭＰ含量明显升高，其中７５ｍＧｙ组ｃＡＭＰ水平为最高（为假照射组的３．７倍ｐ＜０．００１）。而高剂量的对比观察１～４Ｇｙ照射，松果腺ｃＡＭＰ水平呈降低趋势，其中２、４Ｇｙ照射组较假照射组明显减少（ｐ＜０．０５，ｐ＜０．０１）。
Using Kunming mice, whole body irradiation of low dose X-ray dose 50 ~ 500mGy, dose rate of 12.5mGy / min, 24 h after irradiation, detection of cAMP content in pineal gland, the results show that 50 ~ 100mGy X-ray whole body irradiation can make The content of cAMP in pineal gland was significantly increased, of which the cAMP level in 75mGy group was the highest (3.7 times p <0.001 for sham irradiation group). Compared with the high dose, the level of cAMP in pineal gland showed a trend of decrease in 1 ~ 4Gy irradiation, and the 2,4Gy irradiation group was significantly lower than the sham irradiation group (p <0.05, p <0.01).