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为了解抗ICA5 12及GAD6 5自身抗体在汉人中拟诊断为 1型糖尿病的患者血清中的表达情况 ,选择 15例糖尿病酮症或酮症酸中毒的患者及 19例健康者进行血清自身抗体分析 ,发现患者组抗体的阳性率明显高于正常对照组 ;病程 <1年的患者 ,抗体阳性率明显高于病程 >1年者。提示这些自身抗体的检测有利于糖尿病的分型 ,糖尿病病程长短影响抗体的检出率
Serum autoantibodies were analyzed in sera of 15 patients with diabetic ketoacidosis or ketoacidosis and 19 healthy controls in order to find out how the anti-ICA5 12 and GAD6 5 autoantibodies were detected in sera from patients diagnosed with type 1 diabetes in Han Chinese , Found that the positive rate of antibody in patients was significantly higher than the normal control group; duration of <1 year, the antibody positive rate was significantly higher than the duration of> 1 year. Tip detection of these auto antibodies is conducive to the type of diabetes, the duration of diabetes affect the detection rate of antibodies