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本文联合应用多巴胺、酚妥拉明及速尿治疗２１例小儿肾病综合征严重、顽固性水肿，结果显效率为４７６％，有效率为３８１％，总有效率为８５７％。其中１３例患儿在治疗前血清ＢＵＮ和Ｃｒ均有轻度增高，治疗后随着尿量增加，水肿消失，血清ＢＵＮ及Ｃｒ均恢复正常。本文提示：联合应用多巴胺、酚妥拉明及速尿对肾病综合征的严重、顽固性水肿有一定的疗效。
This combined treatment of dopamine, phentolamine and furosemide in 21 cases of severe nephrotic syndrome of children with refractory edema, the results were markedly effective rate was 47 6%, the effective rate was 38 1%, the total effective rate was 85 7% . Serum levels of BUN and Cr were slightly increased in 13 of the 13 children before treatment. After the treatment, urine volume increased, edema disappeared, serum BUN and Cr returned to normal. This article suggests that combined use of dopamine, phentolamine and furosemide have significant effects on severe and refractory edema in nephrotic syndrome.