论文部分内容阅读
目的探讨血浆基质金属蛋白酶-2(MMP-2)与尿微量白蛋白(MAU)的水平检测在糖尿病肾病中的诊断价值。方法 39例糖尿病肾病患者作为观察组,另选取同期进行常规体检的正常人39例作为对照组,比较两组的MMP-2和MAU水平。结果观察组患者的MMP-2水平为(103.76±20.31)ng/ml,较对照组有明显下降,观察组的MAU水平为(56.13±7.94)mg/ml,明显高于对照组水平,组间比较差异均有统计学意义(P<0.05)。结论 MMP-2与MAU在诊断糖尿病肾病方面有较高的灵敏度与准确度,可将其作为糖尿病肾病的早期诊断指标之一。
Objective To investigate the diagnostic value of plasma matrix metalloproteinase-2 (MMP-2) and urinary microalbumin (MAU) levels in the diagnosis of diabetic nephropathy. Methods Thirty-nine patients with diabetic nephropathy were selected as the observation group. Another 39 normal subjects were selected as the control group. The levels of MMP-2 and MAU in the two groups were compared. Results The level of MMP-2 in the observation group was (103.76 ± 20.31) ng / ml, which was significantly lower than that in the control group. The MAU level in the observation group was (56.13 ± 7.94) mg / ml, which was significantly higher than that in the control group The differences were statistically significant (P <0.05). Conclusion MMP-2 and MAU have high sensitivity and accuracy in the diagnosis of diabetic nephropathy, which can be used as one of the early diagnostic indicators of diabetic nephropathy.