论文部分内容阅读
目的:观察推拿对母体乳汁中生长因子(IGF-1、NGF和TGF-β1)浓度影响与哮喘患儿外周静脉血中T细胞亚群CD3、CD4、CD8的变化关系。方法:将慢性缓解期哮喘患儿各100例,严格遵循随机分组的原则将入选病例随机分为治疗组50例和对照组50例。对照组为常规的预防工作,治疗组在基础治疗的基础上,应用母体推拿,各观察3个月,在治疗前、后取母乳和患儿外周血,检测乳汁中IGF-1、NGF和TGF-β1浓度和T细胞亚群CD3、CD4、CD8。结果:治疗后治疗组母体乳汁中IGF-1、NGF和TGF-β1浓度和患儿外周静脉血中T细胞亚群CD3、CD4、CD8与对照组比较,差异有统计学意义(P<0.05),治疗组优于对照组。结论:推拿手法可以通过上调母体乳汁中IGF-1、NGF和TGF-β1浓度,来改善哮喘小儿的免疫功能。
Objective: To observe the relationship between the effects of massage on the concentrations of growth factors (IGF-1, NGF and TGF-β1) in maternal milk and the changes of T cell subsets CD3, CD4 and CD8 in asthmatic children. Methods: 100 cases of asthmatic children with chronic remission were randomly divided into treatment group (n = 50) and control group (n = 50) according to the principle of randomization. The control group was routinely prevented. On the basis of basic treatment, the treatment group used maternal massage and each observation for 3 months. Breast milk and peripheral blood of children were taken before and after treatment, and the levels of IGF-1, NGF and TGF- -β1 concentration and T cell subsets CD3, CD4, CD8. Results: After treatment, the concentrations of IGF-1, NGF and TGF-β1 in peripheral blood and the levels of CD3, CD4 and CD8 in peripheral blood of the treatment group were significantly different from those in the control group (P <0.05) , The treatment group is better than the control group. Conclusion: Massage can improve immune function of asthmatic children by up-regulating the concentrations of IGF-1, NGF and TGF-β1 in maternal milk.