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嗜酸性骨肉芽肿,勒-雪(Letterer-Siwe)二氏病和韩-薛-柯(Hand-Schuller-Christian)三氏征,具有类似的病理基础,同属非脂质性网状内皮增生症(Non-Lipoidreticuloendotheliosis);因而,Lichtenstein统称它们为组织细胞增生症X(Histiocytosis X)。其中嗜酸性骨肉芽肿仅影响骨骼系统,进展缓慢而预后较好,迄1972年,国内报道组织细胞增生症X共43例,其中以1963年刘氏报道的2例比较典型。我们最近遇到1例,累及颅骨、锁骨、
Eosinophilic granuloma, Letterer-Siwe’s disease and Hand-Schuller-Christian trigeminy have similar pathological basis, and belong to non-lipid reticuloendotheliosis (Non-Lipoid reticuloendotheliosis); thus, Lichtenstein collectively referred to them as histiocytosis X (Histiocytosis X). Among them, eosinophilic granulomatosis only affects the skeletal system, with a slow progression and a good prognosis. As of 1972, 43 cases of histiocytosis were reported in China, of which 2 cases were reported by Liu in 1963. We recently encountered a case involving the skull, collarbone,