胰岛素样生长因子结合蛋白-1(IGFBP-1)是已知六种IGFBP中主要的一种。它与胰岛素样生长因子(IGFs)特异性结合,起调节组织和循环中IGF活性的作用,在研究IGF在体内各种生理、病理作用时必须同时加以考虑。国内这方面的研究很少,对正常人群的IGFBP-1水平不甚了解,在我们的系列研究中,作为正常对照,对156例正常人群进行了IGFBP-1水平IRMA分析,现报道如下,供临床参考。 Insulin-like growth factor binding protein-1 (IGFBP-1) is the predominant of the six known IGFBPs. It binds specifically to insulin-like growth factors (IGFs) and plays a role in the regulation of IGF activity in tissues and circulation. It must also be considered when studying the various physiological and pathological effects of IGF in vivo. In our country, there are few studies in this area, and the level of IGFBP-1 in the normal population is poorly understood. In our series, IRMA analysis of IGFBP-1 levels was performed in 156 normal subjects as a normal control in our series of studies as follows Clinical reference.