论文部分内容阅读
目的 :探讨肝硬化患者红细胞免疫功能的变化。方法 :应用免疫学技术测定 31例肝硬化患者红细胞C3b受体 (C3bR)花环试验和免疫复合物花环试验 (IC)及红细胞免疫粘附 (RCIA)调节因子 (RCIA促进因子和RCIA抑制因子 )活性的测定 ,并与 35名健康者作对照。结果 :肝硬化患者C3bR花环率低于正常组 ,而IC花环率高于正常组 (P <0 .0 1) ,RCIA抑制活性明显高于正常组 (P <0 .0 1)。结论 :测定肝硬化患者的红细胞免疫功能 ,对了解其免疫状态具有一定的临床价值。
Objective: To investigate the changes of erythrocyte immune function in patients with cirrhosis. Methods: The activity of erythrocyte C3b receptor (C3bR) rosette and immune complex rosette (IC) and erythrocyte immune adhesion (RCIA) regulators (RCIA and RCIA) were determined in 31 patients with cirrhosis by immunological technique Of the test, and with 35 healthy controls. Results: The C3bR rosette rate in patients with cirrhosis was lower than that in the normal group, while the IC rosette rate was higher in the patients with cirrhosis than in the normal group (P <0.01). The inhibitory activity of RCIA was significantly higher than that in the normal group (P <0.01). Conclusion: The determination of erythrocyte immune function in patients with cirrhosis has some clinical value to understand the immune status.