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巨噬细胞是存在于下呼吸道的最常见的细胞,有人报道高达90%,然而对其在上呼吸道的存在及是否有病理影响却知之甚少,本研究应用特异性免疫组化技术,以季节性变应性鼻炎患者为对象,研究他们在自发和诱发性变应性鼻炎发作前后巨噬细胞密度的改变。要求所有受试者均无支气管和皮肤过敏症状。诱发性变应性鼻炎发作的研究选择牛草花粉过敏的患者10名(9男1女,年龄20～31岁,平均年龄25岁);对照组为3名健康男性(年龄33～41岁)。对受试者每侧鼻腔用浓度为10 000BU/ml的牛草花粉溶液喷雾一次,每次约0.13ml,
Macrophages are the most common cells present in the lower respiratory tract, some reported as high as 90%, but little is known about their presence in the upper respiratory tract and whether they have pathological effects. In this study, specific immunohistochemical techniques were used to measure the seasons Patients with allergic rhinitis were studied for changes in macrophage density before and after the onset of spontaneous and induced allergic rhinitis. All subjects were required to have no bronchial and skin allergy symptoms. Episodes of induced allergic rhinitis The study selected 10 patients (9 males and 1 females, aged 20 to 31 years with a mean age of 25 years) and 3 healthy males (aged 33-41 years) in the control group. The nasal cavity of each side of the subject was sprayed with a solution of bovine pollen at a concentration of 10 000 BU / ml for about 0.13 ml each time,