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目的:分析1例胰岛素制剂致过敏的具体病例,探讨临床药师在参与治疗胰岛素制剂过敏的糖尿病患者中的作用。方法:1例糖尿病患者使用胰岛素治疗过程中出现过敏,多次换用不同种类胰岛素但过敏症状未明显好转,临床药师建议停用含鱼精蛋白的胰岛素,改用甘精胰岛素联合既往口服降糖药物治疗。结果:调整为临床药师建议的降糖治疗方案后,患者住院期间过敏症状较前明显好转,之后未再次出现过敏症状,最终达到满意的降糖治疗效果。结论:临床药师参与患者对胰岛素制剂过敏的治疗,可运用药学知识,准确的判断过敏原,制定个体化的降糖治疗方案,对提高临床诊疗水平及保障患者用药安全性具有帮助和促进作用。
OBJECTIVE: To analyze the specific cases of allergy induced by insulin and explore the role of clinical pharmacists in diabetic patients involved in the treatment of insulin allergy. Methods: One case of diabetes patients with allergies during insulin therapy, many times with different types of insulin but no significant improvement in allergy symptoms, clinical pharmacists recommend the withdrawal of protamine-containing insulin, instead of insulin glargine combined with previous oral hypoglycemic medical treatement. Results: After adjusted to the suggestion of hypoglycemic treatment by clinical pharmacists, the symptoms of allergy in hospitalized patients were obviously better than those before, and the allergic symptoms did not reappear afterwards. Finally, satisfactory hypoglycemic effect was achieved. Conclusion: The clinical pharmacists involved in the treatment of patients with allergic insulin preparations, the use of pharmaceutical knowledge, accurate judgment of allergens, to develop individualized hypoglycemic treatment programs to improve the clinical diagnosis and treatment of patients with medication safety and help play a role in promoting.