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肝内胆汁淤滞症诊断及鉴别较为困难,易致误诊。临床上有将肝内胆汁淤滞误诊为肝外阻塞性黄疸,剖腹探查引起死亡的,教训深刻,深感鉴别诊断的重要性。而且肝内胆汁淤滞症的治疗,目前仍不理想,应用皮质激素治疗,虽少数病人有效,但疗程长,副作用多,有些副作用,如感染、电解质紊乱可招致严重后果。1981年我科连续应用苯巴比妥口服治疗3例肝内胆汁淤滞症的一种淤胆型肝炎,获碍满意疗效,特作报道。
Intrahepatic cholestasis diagnosis and identification more difficult, easy to cause misdiagnosis. Clinically, intrahepatic cholestasis misdiagnosed as extrahepatic obstructive jaundice, laparotomy caused by death, profound lesson, the importance of differential diagnosis. And intrahepatic cholestasis of treatment, is still not ideal, the application of corticosteroids, although a small number of patients effective, but long course, side effects, and some side effects, such as infection, electrolyte imbalance can lead to serious consequences. In 1981, our department continuous application of phenobarbital oral treatment of 3 cases of intrahepatic cholestasis of a cholestatic hepatitis, hinder the satisfactory curative effect, specially made reports.