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采用正交设计法对补中益气汤的小鼠碳粒廓清实验的药效作药物析因,发现与传统认为黄芪是补中益气汤的主药有所不同的是,当归显示出极为优秀的药效;黄芪与白术为最佳药对,而升麻、柴胡、陈皮则无明显作用。提示补中益气汤影响非特异性免疫的最优药物组合应为当归9g、炙甘草6g、人参12g、黄芪9g、白术9g。
Orthogonal design method was used to test the drug efficacy of the test of carbon clearance in mice of Buzhong Yiqi Decoction. It was found that the traditional Chinese medicine that Huangqi is the main drug of Buzhong Yiqi Decoction is different. Excellent efficacy; Astragalus and Atractylodes are the best drugs, while Cimicifuga, Bupleurum, and Chenpi have no significant effect. The optimal drug combination of Buzhong Yiqi Decoction influencing non-specific immunity should be Angelica 9g, Zhigancao 6g, Panax ginseng 12g, Astragalus 9g, Atractylodes macrocephala 9g.