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目的:探究单体素磁共振波谱成像(IH-MRS)在脑肿瘤诊断及与非肿瘤病变鉴别诊断中的应用价值。方法:收集重庆市合川区人民医院2015年3月至2016年2月收治的42例脑肿瘤患者临床资料列入观察组,先后行常规磁共振成像(MRI)和单体素磁共振波谱成像—氢质子磁共振波谱(IH-MRS)检查,另选同期收治的30例非肿瘤病变患者列入对照组,比较各项指标检查情况。结果:观察组中不同类型脑肿瘤周围区域代谢物比值比较以及脑胶质瘤中低级别组和高级别组胶质瘤实质区与周围区代谢物比值比较,差异具有统计学意义(P<0.05);观察组实质区与健康组和对照组脑组织区主要代谢物比值比较,差异具有统计学意义(P<0.05)。结论:借助单因素IH-MRS观察脑肿瘤患者脑代谢改变情况,能够对其做出准确诊断,为临床诊疗提供参考。
Objective: To investigate the value of single-element magnetic resonance spectroscopy (IH-MRS) in the diagnosis of brain tumors and differential diagnosis of non-neoplastic lesions. Methods: The clinical data of 42 patients with brain tumors admitted to Hechuan District People’s Hospital of Chongqing from March 2015 to February 2016 were enrolled in the observation group. The patients were followed up by conventional magnetic resonance imaging (MRI) and single-body magnetic resonance spectroscopy Hydrogen proton magnetic resonance spectroscopy (IH-MRS) examination, the other 30 cases of non-neoplastic lesions were included in the control group, compared the various indicators check the situation. Results: Compared with the ratios of metabolites in different types of brain tumors in the observation group and the ratios of the metabolites in the gliomas of the low grade group and the high grade group to the surrounding area, the difference was statistically significant (P <0.05 ). The ratio of the main metabolites in the observation area and the brain tissue of the healthy group and the control group was significantly different (P <0.05). Conclusion: The single factor IH-MRS can be used to observe the changes of brain metabolism in patients with brain tumors, which can make accurate diagnosis and provide reference for clinical diagnosis and treatment.