我国是胃癌病发国,以沿海地区及黄河中游(河套地区及河西走廊)最为严重,其他地区亦有散在的流行点。大致上沿海比内地为重,华中比华南华北为重。全国平均年死亡率约15/10万,上海地区约45/10万,严重的流行地区如甘肃武威,高达100/10万以上。十多年来,我国在胃癌研究上已经取得重大进展,本文简要介绍国内外在胃癌基础和临床方面的研究现状。 China is a country suffering from gastric cancer, with the most serious coastal areas and the middle reaches of the Yellow River (Hetao and Hexi corridors). There are also scattered spots in other areas. The coast is generally heavier than the mainland, and Huazhong is more important than South China and North China. The average annual national mortality rate is about 15 to 100,000, and that of the Shanghai area is about 45 to 100,000. The severely endemic areas such as Wuwei in Gansu Province are as high as 100/100,000. For more than a decade, China has made significant progress in the study of gastric cancer. This article briefly introduces the research status of basic and clinical aspects of gastric cancer at home and abroad.