青霉素皮试在我国一直作为能否使用青霉素的判断标准.自50年代起国外就开始不作皮试,采用po青霉素,不良反应率很低.对po青霉素皮肤试验的必要性,卫生部药政局非常关心与谨慎.我院受卫生部委托,对1000例病人进行了不作皮试po美格西林(phenoxymethyl-penicillin,青霉素V)片的疗效与安全性评价.1 材料与方法1.1 病例来源1996年1月～1997年1月由我院临床药理室负责,安排临床各科对门急诊及住院病 Penicillin skin test in our country has been used as a criterion for the use of penicillin.From the 50’s since the beginning of foreign skin test, the use of po penicillin, adverse reaction rate is very low .Pecin penicillin skin test necessity, the Ministry of Health Pharmaceutical Council very Care and cautious .In our hospital commissioned by the Ministry of Health, 1000 cases of patients were not skin test pomecillin (phenoxymethyl-penicillin, penicillin V) tablets efficacy and safety evaluation .1 Materials and methods 1.1 cases source 1996 1 January ~ January 1997 by our hospital clinical pharmacology room responsible for arranging clinical departments of emergency and inpatient