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牙膏是一个很方便且容易得到的载体,它可以运载诸如抗生素、氟化物和活性因子等成分来控制和预防多种常见的口腔疾病。新型亚锡-氟化钠牙膏(1.45×10-3ppm F-)控制和预防多种主要口腔疾病的功效已经在全球多个地区得到实验室和临床验证。在中国被命名为佳洁士Pro-Health健康专家系列牙膏,在部分欧洲市场的商品名为blend-a-med Pro-Ex-pert,本文综述了新型亚锡-氟化钠牙膏的实验室和临床试验研究情况。研究指出新型亚锡-氟化钠牙膏的临床效果优于阴性对照组,与阳性对照组的临床效果相当甚至更好,结果表明该产品具有防龋能力,同时可以有效减少牙菌斑、缓解牙本质敏感、抑制外源性色素沉着以及改善口腔异味。
Toothpaste is a convenient and easily available carrier that can carry ingredients such as antibiotics, fluoride and active ingredients to control and prevent many common oral diseases. The efficacy of the new stannous-sodium fluoride toothpaste (1.45 × 10-3ppm F-) in the control and prevention of many major oral diseases has been demonstrated both in the laboratory and in clinics in many regions of the world. Named as Crest Pro-Health Toothpaste in China, this product is called blend-a-med Pro-Ex-pert in some European markets. This article reviews the laboratory and clinical trials of the new stannous-sodium fluoride toothpaste Research situation The research indicates that the clinical effect of the new stannous-sodium fluoride toothpaste is better than that of the negative control group, and the clinical effect is even better than that of the positive control group. The results show that the product has anti-caries ability and can effectively reduce plaque and teeth Essential sensitivity, inhibition of extrinsic pigmentation and improve oral odor.