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目的:探讨胆结石合并胆管癌的临床诊断方法、临床治疗措施和烷化剂治疗该病的疗效。方法:以我院自2008年3月到2010年3月收治的58例胆结石合并胆管癌的患者为研究对象,回顾性分析其临床资料,分析总结患者诊断的方法和治疗的措施,研究诊断的有效手段和临床治疗效果。结果:58例患者入院经过B超、CT、MRCP、肿瘤标记物等检查,被确诊为胆结石合并胆管癌患者33例,其余患者经过手术治疗后的病理证实为胆结石合并的胆管癌。结论:胆结石和胆管癌的发生有着密切的关系,对年龄>40岁的患者且病史长、肝胆管反复感染的胆结石患者,短时间严重消瘦和肝区疼痛难以消除的患者,要警惕其并发胆管癌的可能[1]。
Objective: To explore the clinical diagnosis of gallstone with cholangiocarcinoma, clinical treatment measures and the efficacy of alkylating agents in the treatment of the disease. Methods: A total of 58 patients with cholecystolithiasis admitted to our hospital from March 2008 to March 2010 were retrospectively analyzed, and the methods of diagnosis and treatment were summarized and analyzed. The diagnosis The effective means and clinical treatment effect. Results: Fifty-eight patients were diagnosed as cholecystolithiasis with cholangiocarcinoma by ultrasonography, CT, MRCP and tumor marker. The remaining patients were pathologically confirmed as cholecystolithiasis with cholangiocarcinoma. Conclusion: Gallstones and cholangiocarcinoma are closely related. Patients with a history of 40 years and patients with recurrent gallbladder and bile duct stones who suffer severe shortness of time and pain in the liver area should be wary of it The possibility of concurrent cholangiocarcinoma [1].