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糖尿病周围神经病变是糖尿病常见的并发症,严重影响患者的生活质量。现有的治疗用药主要包括:醛糖还原酶抑制剂、糖基化产物抑制剂和N-乙酰基-L-肉毒碱等针对代谢异常的药物;地诺前列酮、阿司匹林、西洛他唑和舒洛地特等改善微循环的药物;α硫辛酸和依达拉奉等抗氧化药物;甲钴胺和神经营养因子等营养神经药物以及减轻疼痛等对症治疗。
Diabetic peripheral neuropathy is a common complication of diabetes, seriously affecting the quality of life of patients. Existing therapeutic drugs include: aldose reductase inhibitors, glycosylation inhibitors and N-acetyl-L-carnitine and other drugs for metabolic disorders; dinoprostone, aspirin, cilostazol And sulodexide and other drugs to improve microcirculation; alpha lipoic acid and edaravone and other antioxidant drugs; mecobalamin and neurotrophic factors and other neurotrophic drugs and relieve pain and other symptomatic treatment.