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鲨鱼软骨提取物(sharkcartilageactiveextract,SCAE)在体外细胞实验中,当浓度为50μg/ml时,对肿瘤细胞的抑制率是50.2%~60%。在小鼠移植瘤实验中表明,SCAE作用最佳的是分子量1×104~5×104部位。小鼠口服SCAE24~72mg/d的抑瘤率是54%~67%,小鼠注射SCAE6~18mg/d的抑癌率是67%~82.2%。SCAE有溶于水,用量小等特点。
In shark cartilage active extract (SCAE), in vitro cell experiments, when the concentration was 50 μg/ml, the inhibition rate of tumor cells was 50.2% to 60%. In mouse xenograft experiments, the best effect of SCAE was at a molecular weight of 1 x 104 to 5 x 104 sites. The inhibition rate of oral SCAE from 24 to 72 mg/d in mice was 54% to 67%, and the tumor suppression rate in mice injected with SCAE from 6 to 18 mg/d was 67% to 82.2%. SCAE is soluble in water and has a small amount of usage.