所谓“慢性持续性咳嗽”(CPC)通常是指咳嗽症状持续3周以上,经常规治疗效果不佳,且病因未明者,为呼吸科常见的就诊原因。在美国,不吸烟人群中成人慢性咳嗽发生率为14%~23%[1],故研究CPC有其临床价值,由于许多患者仅有咳嗽症状,难以发现病因方面的客观证据,经常延误诊断。迄今, The so-called “chronic persistent cough” (CPC) usually refers to the symptoms of cough for more than 3 weeks, the conventional treatment ineffective, and the etiology, is a common cause of respiratory consultations. In the United States, the incidence of chronic cough among adults in non-smokers ranges from 14% to 23% [1]. Therefore, the study of CPC has its clinical value. Because many patients have only cough symptoms, it is difficult to find objective evidence of the cause of the disease and diagnosis is often delayed. so far,