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[目的]观察健脾益气方、保肛手术联合化疗治疗低位直肠癌疗效。[方法]使用前瞻性设计,将31例门诊及住院患者保肛手术:术前纠正水和电解质平衡,乙状结肠系膜游离至下动脉根部,于肠系膜下动脉根部2cm处切断并游离,直肠及系膜锐性分离,与提肛肌同水平,保证切除平面在肿块直肠远端>2cm,直肠及固有筋膜组织完整切除,术后常规化疗;健脾益气方(黄芪12g,白花蛇舌草30g,薏苡仁、当归各12g,苍术10g,白术12g,大枣、白芍各10g,首乌12g;口干唇燥、大便干结加沙参;畏寒畏冷、四肢浮肿加用肉桂、干姜),1剂/d,水煎200m L,早晚口服。治疗21d为1疗程。观测临床症状、直肠癌病灶、不良反应。治疗1疗程,判定疗效。[结果]显效16例,有效13例,无效2例,总有效率93.55%。[结论]健脾益气方、保肛手术联合化疗治疗低位直肠癌疗效满意,无副作用,值得推广。
[Objective] To observe the effect of Jianpi Yiqi prescription and anal sphincter preservation combined with chemotherapy on low rectal cancer. [Methods] With prospective design, 31 outpatients and inpatients were given anal sphincter preservation surgery. Water and electrolyte balance were corrected before operation. The sigmoid mesangial was dissociated to the root of inferior arteries and cut off at 2cm from the root of inferior mesenteric artery. Membrane sharp separation, and levator ani muscle with the same level to ensure that the resection plane in the distal rectal> 2cm, rectal and natural fascia complete resection, postoperative chemotherapy; Jianpi Yiqi Fang (Astragalus 12g, Hedyotis diffusa 30g, Coix Seed, Angelica 12g, Atractylodes 10g, Atractylodes 12g, jujube, white peony root of the 10g, Radix 12g; mouth dry lips, dry stool Gaza ginseng; chills, limbs edema plus cinnamon, ginger ), 1 / d, decoction 200m L, morning and evening oral. Treatment of 21d for a course of treatment. Observation of clinical symptoms, rectal cancer lesions, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] 16 cases were markedly effective, 13 cases were effective and 2 cases were ineffective. The total effective rate was 93.55%. [Conclusion] Jianpi Yiqi Recipe and anal sphincter preservation combined with chemotherapy are effective in treating low rectal cancer with no side effects and are worthy of popularization.